Web19 de jul. de 2024 · Abstract. T cells express T cell receptors (TCRs) composed of somatically recombined TCRα and TCRβ chains, which mediate recognition of major … Web21 de mar. de 2024 · In chronic myeloid leukemia (CML), the duration of deep molecular response (MR) before treatment cessation (MR4 or deeper, corresponding to BCR-ABL1 ≤ 0.01% on the International Scale (IS)) is considered as a prognostic factor for treatment free remission in stopping trials. MR level determination is dependent on the sensitivity of the …
High BCR–ABL/GUSIS Levels at Diagnosis of Chronic Phase CML …
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Desirable performance characteristics for BCR-ABL measurement …
Web12 de dez. de 2024 · B cell receptor (BCR) sequencing is a powerful tool for interrogating immune responses to infection and vaccination, but it provides limited information about … Web15 de mar. de 2024 · For high-risk BCR, early restaging (including modern imaging) and early salvage therapy are recommended. It has repeatedly been shown that commercially available genomic tests such as Decipher can identify patients at risk of metastatic progression after primary treatment and influence treatment decision-making [20], [21], [22]. Web16 de nov. de 2012 · Correlations between high BCR-ABL transcripts at diagnosis and unsatisfactory IM responses were much stronger using GUS in place of ABL as a … port term insurance