WebLipodermatosclerosis is fibrosis found in the layers of the skin in the lower legs and is commonly seen in CVI. It forms a constrictive band of hard fibrotic tissue around the ankle. This changes the shape of the lower legs to appear like an upside-down bowling pin, or champagne bottle, with small ankles and large, swollen calves. WebLipodermatosclerosis most commonly occurs in people with raised pressure in the leg veins (venous hypertension or venous incompetence). The raised pressure causes fluid and proteins to leak out of the veins and causes fibrosis and inflammation of the underlying skin. There may also be a lack of oxygen and nutrient delivery to the tissue.
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